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Four-year follow-up of patients with imatinib-resistant or intolerant chronic myeloid leukemia receiving

Xiaojun Huang, Qian Jiang, Jianda Hu, Jianyong Li, Jie Jin, Fanyi Meng, Zhixiang Shen, Ting Liu, Depei Wu, Jianmin Wang, Jianxiang Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 344-353 doi: 10.1007/s11684-018-0639-7

Abstract: This report from the 4-year follow-up revealed that 73% of 59 patients in chronic phase (CML-CP) andAll CML-CP patients who achieved MCyR after a 4-year follow-up also achieved a complete cytogenetic responsewith CML-AP was 64% (16/25), with three CML-AP patients achieving CHR between 18 months and 4 years of follow-upThese long-term follow-up data continue to support dasatinib as a second-line treatment for Chinese patients

Keywords： chronic myeloid leukemia (CML)     dasatinib     tyrosine kinase inhibitor     long-term follow-up    

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Long-term results of suppressing thyroid-stimulating hormone during radiotherapy to prevent primary hypothyroidism

Maura Massimino, Marta Podda, Lorenza Gandola, Emanuele Pignoli, Ettore Seregni, Carlo Morosi, Filippo Spreafico, Andrea Ferrari, Emilia Pecori, Monica Terenziani

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 101-107 doi: 10.1007/s11684-020-0752-2

Abstract: From 14 days before and up to the end of radiotherapy, patients were administered L-thyroxine checkingDuring follow-up, blood tests and ultrasound were repeated; primary hypothyroidism was considered an

Keywords： iatrogenic primary hypothyroidism     late effects of radiotherapy     long-term follow-up     medulloblastoma     Hodgkin    

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Technetium-99m-sestamibi SPECT for the diagnosis and follow-up of nasopharyngeal carcinoma

Jing CHEN MD, Guang-Yuan HU MD, Guo-Qing HU MD, Hua WU PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 96-100 doi: 10.1007/s11684-010-0001-1

Abstract: Histopathologic results and/or clinical follow-up data (over 18 months) were used as the golden standardThe combination of CT and Tc-MIBI SPECT can give more accurate diagnosis in the follow-up of NPC.

Keywords： nasopharyngeal carcinoma     diagnosis     follow-up    

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Chimeric antigen receptor T-cell therapy: a promising treatment modality for relapsed/refractory mantle cell lymphoma

Ping Li, Ningxin Dong, Yu Zeng, Jie Liu, Xiaochen Tang, Junbang Wang, Wenjun Zhang, Shiguang Ye, Lili Zhou, Alex Hongsheng Chang, Aibin Liang

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 811-815 doi: 10.1007/s11684-020-0740-6

Abstract: Bruton’s tyrosine kinase have shown efficacy for relapsed or refractory (r/r) MCL but often have short-termHowever, long-term safety and tolerability associated with CAR T-cell therapy are not defined well, especiallyIn this report, we described a 70-year-old patient with r/r MCL with 48-month duration of follow-up whoachieved long-term remission after CAR T-cell therapy.

Keywords： anti-CD19 chimeric antigen receptor T cells     mantle cell lymphoma     relapsed or refractory     long-term follow-up    

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The first year follow-up after colorectal adenoma polypectomy is important: A multiple-center study in

Qin-Yan GAO, Hui-Min CHEN, Jing-Yuan FANG, Jian-Qiu SHENG, Ping ZHENG, Cheng-Gong YU, Bo JIANG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 436-442 doi: 10.1007/s11684-010-0200-9

Abstract: The aim of the present research is to investigate how long after polypectomy follow-up should take andThey were divided into 4 groups: group A (follow-up≤1 year after polypectomy), group B (follow-up2–3 years after polypectomy), group C (follow-up 4–5 years after polypectomy), and groupB, 78.07% in group C, and 87.12% in group D, which indicated an increased tendency with a prolonged follow-upIt may not be necessary to do the follow-up examination during the second and third years, but after

Keywords： colorectal adenoma     polypectomy     follow-up     recurrence     risk factor    

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A 7-year follow-up study of the features and transformations of elderly male patients with OGTT-1h hyperglycemia

TIAN Hui, LI Chunlin, ZHONG Wenwen, PAN Changyu, LU Juming, CAO Xiutang

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 396-399 doi: 10.1007/s11684-008-0076-0

Abstract: Seven years of follow-up visits were performed on 189 elderly male outpatients with OGTT-1h HG and dataFollow-up visits revealed that 19 patients with OGTT-1h HG were diagnosed with diabetes (10.1%), 78 patients

Keywords： special attention     prevalence     unchanged     dyslipidemia     elderly    

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therapeutic efficacy of ursodeoxycholic acid in Chinese patients with primary biliary cirrhosis: a 2-year follow-up

Jiangyi Zhu, Yongquan Shi, Xinmin Zhou, Zengshan Li, Xiaofeng Huang, Zheyi Han, Jianhong Wang, Ruian Wang, Jie Ding, Kaichun Wu, Ying Han, Daiming Fan

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 255-263 doi: 10.1007/s11684-012-0227-1

Abstract:

The efficacy of ursodeoxycholic acid (UDCA) on long-term outcome of primary biliary cirrhosis (PBCday-1) and followed up for 2 years to evaluate the changes of symptoms, laboratory valuesThese data suggest that, when treated in earlier stage, patients in long-term administration of UDCA

Keywords： primary biliary cirrhosis     ursodeoxycholic acid     Chinese     biochemical response     therapeutic efficacy    

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Stabilization-based soil remediation should consider long-term challenges

Zhengtao Shen, Zhen Li, Daniel S. Alessi

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 2, doi: 10.1007/s11783-018-1028-9

Abstract: However, there are emerging challenges regarding the long-term performance of the technology, which maystem from a research gap regarding the development of accurate, quantitative laboratory simulations of long-termTherefore, field trials coupled with long-term monitoring are critical to further verify conditions underSustainability is also an important factor affecting the long-term stability of site remediation.

Keywords： Stabilization     Soil remediation     Long-term     Trace metals    

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A perspective of “Nuclear Hot Spring” for long-term sustainable economy of the world

Yingzhong LU

Frontiers in Energy 2011, Volume 5, Issue 4,   Pages 349-357 doi: 10.1007/s11708-011-0168-4

Abstract: The rapid growth of human economy in the late 20th century gave rise to great concern over sustainability of the world. A pessimistic “Full World Model” forecasts that human economy could not develop further. The nuclear fission (and fusion later), however, could release huge amount of energy to create sufficient useful material resources and turn the said pessimistic modelinto a new optimistic “Sustainable World Model”.The dilemma of nuclear energy (Military Giant vs. Civil Dwarf) jeopardizes its performance as a “Technologic Fixer”. According to Mother Nature’s teachings, the elimination of the root-causes of the design-based risk factors could solve this problem. Recent technology break-through from inherent safety to natural safety has been made in China. The proposed full-power natural circulation “Nuclear Hot Spring (NHS)” reactor could operate solely on natural forces without complex man-made coolant circulation equipment and human-operated control systems. The cheap, unlimited supply of energy from nuclear energy could change the geopolitics forever, and finally eliminate the root-causes of most international and regional conflicts.

Keywords： natural safety reactor     full power natural circulation     sustainable world economy    

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Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1684-2

Abstract:

● This study explored the long-term association by double robust

Keywords： Air pollution     Cerebrovascular disease     Incidence     Long-term exposure     Doubly robust additive model    

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Effects of coarse and fine aggregates on long-term mechanical properties of sea sand recycled aggregate

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 3,   Pages 754-772 doi: 10.1007/s11709-021-0711-2

Abstract: Typical effects of coarse and fine aggregates on the long-term properties of sea sand recycled aggregateFinally, an analytical expression is suggested to construct the long-term stress–strain curve of SSRAC

Keywords： aggregate concrete     recycled coarse aggregate replacement percentage     sea sand chloride ion content     long-term    

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Long-term adaptive evolution of

Yong Xiao, Changye Xiao, Feng Zhao

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1182-8

Abstract: remains uncertain how microorganisms acquire resistance to high concentrations of pollutants during long-termS. oneidensis MR-1 is improved by acclimation, as well as a genetic understanding of the impact of long-term

Keywords： Environmental biotechnology     Acclimation     Chromate resistance     Efflux pumps     Detoxification    

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Elucidate long-term changes of ozone in Shanghai based on an integrated machine learning method

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 11, doi: 10.1007/s11783-023-1738-5

Abstract:

● A novel integrated machine learning method to analyze O3 changes is proposed.

Keywords： Ozone     Integrated method     Machine learning    

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CONCENTRATIONS AND FLUXES OF DISSOLVED NUTRIENTS IN THE YANGTZE RIVER: LONG-TERM TRENDS AND ECOLOGICAL

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 559-567 doi: 10.15302/J-FASE -2020344

Abstract:

Intensifying human activity in the Yangtze River basin has substantially increased nutrient concentrations in the Yangtze River Estuary, leading to degradation of the coastal environment. Analysis of nutrient determinations published over the past 50 years reveals a gradual decreasing trend in the concentrations and fluxes of dissolved silicate (DSi). However, both dissolved inorganic nitrogen (DIN) and dissolved inorganic phosphate (DIP) concentrations have increased significantly since the 1970s. The frequency of and area covered by red tide outbreaks have increased greatly during this period, mainly due to changes in nutrient supply ratios [i.e., N/P (DIN/DIP), N/Si (DIN/DSi), P/Si (DIP/DSi)]. A strong correlation was found between the riverine DIN fluxes and the estimated DIN inputs from the major N sources, particularly fertilizers and atmospheric deposition. The data provide a comprehensive assessment of nutrients in the Yangtze River basin and their ecological impacts and indicate a potentially significant influence of atmospheric deposition on DIN loadings and fluxes.

 

Keywords： atmospheric deposition / ecological impacts / nitrogen sources / nutrients / Yangtze delta    

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Mycophenolate mofetil or tacrolimus compared with azathioprine in long-term maintenance treatment for

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 799-807 doi: 10.1007/s11684-021-0849-2

Abstract: The median follow-up time was 60 months.Long-term maintenance therapies with MMF or TAC might have similarly low rates of renal relapse and similar

Keywords： lupus nephritis     mycophenolate mofetil     tacrolimus     maintenance therapy    

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Title Author Date Type Operation

Four-year follow-up of patients with imatinib-resistant or intolerant chronic myeloid leukemia receiving

Xiaojun Huang, Qian Jiang, Jianda Hu, Jianyong Li, Jie Jin, Fanyi Meng, Zhixiang Shen, Ting Liu, Depei Wu, Jianmin Wang, Jianxiang Wang

Journal Article

Long-term results of suppressing thyroid-stimulating hormone during radiotherapy to prevent primary hypothyroidism

Maura Massimino, Marta Podda, Lorenza Gandola, Emanuele Pignoli, Ettore Seregni, Carlo Morosi, Filippo Spreafico, Andrea Ferrari, Emilia Pecori, Monica Terenziani

Journal Article

Technetium-99m-sestamibi SPECT for the diagnosis and follow-up of nasopharyngeal carcinoma

Jing CHEN MD, Guang-Yuan HU MD, Guo-Qing HU MD, Hua WU PhD,

Journal Article

Chimeric antigen receptor T-cell therapy: a promising treatment modality for relapsed/refractory mantle cell lymphoma

Ping Li, Ningxin Dong, Yu Zeng, Jie Liu, Xiaochen Tang, Junbang Wang, Wenjun Zhang, Shiguang Ye, Lili Zhou, Alex Hongsheng Chang, Aibin Liang

Journal Article

The first year follow-up after colorectal adenoma polypectomy is important: A multiple-center study in

Qin-Yan GAO, Hui-Min CHEN, Jing-Yuan FANG, Jian-Qiu SHENG, Ping ZHENG, Cheng-Gong YU, Bo JIANG,

Journal Article

A 7-year follow-up study of the features and transformations of elderly male patients with OGTT-1h hyperglycemia

TIAN Hui, LI Chunlin, ZHONG Wenwen, PAN Changyu, LU Juming, CAO Xiutang

Journal Article

therapeutic efficacy of ursodeoxycholic acid in Chinese patients with primary biliary cirrhosis: a 2-year follow-up

Jiangyi Zhu, Yongquan Shi, Xinmin Zhou, Zengshan Li, Xiaofeng Huang, Zheyi Han, Jianhong Wang, Ruian Wang, Jie Ding, Kaichun Wu, Ying Han, Daiming Fan

Journal Article

Stabilization-based soil remediation should consider long-term challenges

Zhengtao Shen, Zhen Li, Daniel S. Alessi

Journal Article

A perspective of “Nuclear Hot Spring” for long-term sustainable economy of the world

Yingzhong LU

Journal Article

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

Journal Article

Effects of coarse and fine aggregates on long-term mechanical properties of sea sand recycled aggregate

Journal Article

Long-term adaptive evolution of

Yong Xiao, Changye Xiao, Feng Zhao

Journal Article

Elucidate long-term changes of ozone in Shanghai based on an integrated machine learning method

Journal Article

CONCENTRATIONS AND FLUXES OF DISSOLVED NUTRIENTS IN THE YANGTZE RIVER: LONG-TERM TRENDS AND ECOLOGICAL

Journal Article

Mycophenolate mofetil or tacrolimus compared with azathioprine in long-term maintenance treatment for

Journal Article